Figure 2.

The effects of ZG02-ME administration on blood lipid levels, body weight gain, and food consumption in diabetic-obese (db/db) mice. The db/m mice were intragastrically administrated daily with normal saline containing 0.01% DMSO, as the vehicle, for four weeks (normal control). The db/db mice were intragastrically administrated daily with vehicle (vehicle control) or ZG02-ME (1, 3, 5 mg/kg body weight), respectively, for four weeks. (A) The total cholesterol (TC), triglyceride (TG), and low-density lipoprotein (LDL-C) levels in blood serum were measured as described in the methods; (B) Body weight and food intake were continuously measured from initial to final administration. Data are shown as mean ± SD of (n = 8). ^# p < 0.05 vs. normal control, and * p < 0.05 vs. vehicle-treated control as determined by one-way Student’s t-test.