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Effect of RBP on endothelium-dependent vasorelaxation induced by acetylcholine and endothelium-independent vasorelaxation induced by sodium nitroprussside in aortic rings pre-contracted with phenylephrine (A,C) and mesenteric artery beds pre-contracted with methoxamine (B,D). Data are mean values ± SEM; (n = 8/group), * p < 0.05 vs. sham-operated group, # p < 0.05 vs. 2K-1C group; Rice bran peptides, RBP; Maximal response, Emax; half maximal effective concentration, EC50.
