FIG. 4.

Effects of methylphenidate (MPD) on larval swim activity following a transition into darkness in zebrafish developmentally exposed to deltamethrin (DLM). Data points are presented as mean distance traveled (mm) ± S.E.M. in 5-min time bins during 25-min sessions (n = 76–97). A 3-way ANOVA was used to determine if there was a significant effect of deltamethrin, methylphenidate, and time on larval swim activity as well as an interaction (deltamethrin ×methylphenidate × time). As determined by Holm-Sidak multiple comparisons, * indicates that distance traveled across time in deltamethrin exposed animals are significantly different from vehicle control exposed animals (P ≤ 0.05). # indicates that there is a significant effect of methylphenidate on the distance traveled across time within vehicle control exposed animals (P ≤ 0.05). † indicates that there is a significant effect of methylphenidate on the distance traveled across time within deltamethrin exposed animals (P ≤ 0.05).