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. 2015 Jul 28;6:382. doi: 10.3389/fimmu.2015.00382

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Copyright © 2015 Aas-Hanssen, Thompson, Bogen and Munthe.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Analysis of CDR3 from IgVH of neonatal sequences, role of somatic mutations. We compared IgVH CDR3/microorganism matches in two data sets derived from the highly mutated DTG sequences and neonatal sequences from L2-TG mice. (A) Exact matches per sequence are shown in contiguous microbial sequences. (B) Hits matches/mismatches in the microbial proteome are shown (aa length-matches/mismatches, denoted as in Figure 1). (C) Matches including mismatches compared to Herpesviridae proteome, hits normalized to the number of input sequences are shown.