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. 2015 Jun 1;5(2):277–282. doi: 10.15171/apb.2015.038

Table 4. Kinetic models used for analysis of selected formulations release data.

Formulation code Zero order (F=kt) First order (ln (1-F) = - kft) Higuchi (F= k t0.5)
MRSQ K MRSQ K MRSQ K
A1 0.955 0.144 0.986 0.001 0.996 2.865
A2 0.960 0.192 0.998 0.004 0.996 4.811
A3 0.973 0.143 0.997 0.002 0.999 3.558
A4 0.915 0.001 0.958 0.002 0.979 0.031
A5 0.978 0.001 0.995 0.001 0.993 0.283
A6 0.979 0.003 0.982 0.004 0.983 0.008
B1 0.978 0.003 0.999 0.002 0.998 0.329
B2 0.990 0.001 0.999 0.002 0.990 0.282
B3 0.960 0.001 0.990 0.002 0.998 0.033
B4 0.957 0.001 0.976 0.001 0.998 0.205
B5 0.972 0.004 0.997 0.003 0.998 0.034
B6 0.954 0.001 0.974 0.001 0.994 0.184
C1 0.974 0.001 0.999 0.002 0.999 0.032
C4 0.977 0.001 0.977 0.002 0.999 0.032
Adcortyl® 0.985 0.001 0.998 0.002 0.996 0.349

F denotes fraction of drug released up to time t.