Figure 1.

Role of translation factors in canonical eukaryotic translation and interactions with viral RNAs or proteins. (A) Simplified diagram of translation initiation. Key initiation factors are shown as well as the best characterized interactions with viral components. eIF3 is shown as a complex of subunits. Please refer to the text for details of the specific isoform of eIF4E or eIF4G or specific eIF4A-like helicase recruited by various plant viruses; (B) Simplified diagram of translation elongation. Key elongation factors are shown as well as the best characterized interactions with viral components.