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The different steps of the rhabdovirus cycle inhibited by interferon (IFN)-stimulated gene (ISG) products. IFN-inducible transmembrane (IFITM) proteins block viral entry, CH25h impairs the virus cell-fusion step by inducing cellular membrane changes, MxA inhibits primary transcription, ISG20 and ProMyelocytic Leukemia (PML) inhibit secondary transcription, protein kinase (PKR) and IFIT proteins inhibit viral translation and Tetherin prevents release of virions from the cell.
