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. 2015 Jul 17;7(7):3891–3909. doi: 10.3390/v7072803

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© 2015 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

The serum neutralizing antibody responses to CA16 viruses prepared with different inactivation methods. Groups of ICR mice (n = 6) were immunized with purified inactivated CA16 with or without adjuvant, or with adjuvant only as a control. Virus represents as inactivated by BPL and without adjuvant, BPL represents as inactivated by BPL and with adjuvant, Formalin represents as inactivated by formalin and with adjuvant Symbols represent reciprocal neutralizing antibody titers from groups of six animals. Neutralization titers (Y-axis) are plotted on a logarithmic scale.