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Amino acid alignment of pigeon, goose, duck and zebra finch RIG-I. Black shading indicates amino acid identity, and the green frame indicates the phosphorylation sites. The blue frame denotes ubiquitination sites, and the red frame indicates the ATP-binding motif. The yellow frame indicates the critical residue for the interaction between CARDs and HEL2i, and the orange frame denotes the critical residues for RNA ligand binding.
