Distributions of SNP densities between basic genomes. (A) Distribution of perfectly aligned 1-kbp segments from the set of 3,769 as a function of average SNP density δ for five basic-genome pairs: group A strain MG1655 aligned with ETEC (A–A, Δ = 0.38%, black triangles); B–DL (A–A, Δ = 0.72%, brown squares); SE11 (A–B1, Δ = 1.16%, red triangles); O157 (A–E, Δ = 1.56%, blue circles); and IHE (A–B2, Δ = 2.54%, green diamonds). (B) Distributions of SNP density as a function of δ as predicted by the computational model given in Supporting Information for pairs of genomes having the same average SNP densities Δ as the five genome pairs in A.