Fig. S6.

CD8⁺ T cells with inhibited expression of lncRNA-CD244 show greater production of INF-γ and TNF-α. (A) Representative CBA assays of CD8⁺ T cells purified from PBMCs of a patient with active TB showing that, compared with transduction of LV-Ctrl or treatment with transduction medium, transduction of LV vector encoding GFP and shRNA targeting lncRNA-CD244 (LV-lncRNA-CD244) in CD8⁺ T cells induced a significant increase of concentration of IFN-γ and TNF-α. (B–D) Pooled data showing the concentrations of IFN-γ, TNF-α, and IL-6 upon transfection of indicated LV vectors (n = 8). Error bars represent SEM. Shown is a representative of at least three independent experiments.