Table S1.

Details of P450cam samples used for NMR experiments

No.	Labeling scheme	Tag	Percentage assigned, %	[P450cam], μM	Camphor*	Buffer conditions
1	15N 13C 2H	—	74	530	+	20 mM Hepes (pH 7.5), 100 mM NaCN
2	15N 2H	Lu–CLaNP-7	42	100	+	50 mM Tris⋅HCl (pH 7.4), 100 mM KCl
3	15N 2H	Yb–CLaNP-7	42	100	+	50 mM Tris⋅HCl (pH 7.4), 100mM KCl
4	15N-Leu	Lu–CLaNP-7	64	175	+	20 mM Hepes (pH 7.5), 200 mM KCl
5	15N-Leu	Yb–CLaNP-7	45	300	+	20 mM Hepes (pH 7.5), 200 mM KCl
6	15N 2H	—	55	340	−	20 mM Hepes (pH 7.5), 100 mM KCN
7	15N-Leu	Lu–CLaNP-7	55	175	−	20 mM Hepes (pH 7.5)
8	15N-Leu	Yb–CLaNP-7	40	175	−	20 mM Hepes (pH 7.5)

^*Presence/absence of camphor [1 mM, 1% (vol/vol) methanol].