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. 2015 Jul 28;5:12621. doi: 10.1038/srep12621

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(A) Averaged hemodynamic time series from regions of interest selected from different vascular compartments for anesthetized mice (n = 6) under 100% oxygen and the same mice (B), under medical air. (C) Averaged hemodynamic time series from a separate group of head fixed awake mice (n = 4). (D) Predicted blood oxygen level-dependent (BOLD) functional magnetic resonance imaging (fMRI) response for all three conditions, using parenchyma time series data as input to a biophysical model. All data shown as mean ± s.e.m.