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. 2015 Jul 28;5:12621. doi: 10.1038/srep12621

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Copyright © 2015, Macmillan Publishers Limited

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(A,B) Summary of averaged Hbt and Hbr time series for the parenchyma region from anesthetized and awake mice. (C,D) Onset of the hemodynamic response and time to 10% of the first peak is shown for Hbt and Hbr. A linear line fit to the initial rising slope was used for estimating the response onset. For statistical analysis, two tailed, unpaired t-test (anesthetized, n = 6, vs awake n = 4). Data shown as mean ± s.e.m.