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. Author manuscript; available in PMC: 2016 Aug 1.
Published in final edited form as: Free Radic Biol Med. 2015 May 19;85:288–294. doi: 10.1016/j.freeradbiomed.2015.05.011

Figure 4. Cofilin is activated by a Nox4 dependent mechanism.

Figure 4

HASMCs were transfected with siRNA against Nox4 or non-targeting siRNA 3 days before initiating 2 hours of cyclic mechanical stimulation or static control conditions. Samples were processed for western blotting using specific antibodies for cofilin and p-cofilin. Representative image and bar graphs (mean ± SE) of at least 5 independent experiments performed are shown. * and ¥ Indicate P<0.05 for stretch and siNox4, respectively.