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. Author manuscript; available in PMC: 2016 Aug 1.
Published in final edited form as: Free Radic Biol Med. 2015 May 19;85:288–294. doi: 10.1016/j.freeradbiomed.2015.05.011

Figure 6. A constitutively active cofilin mutant reverses the phenotype induced by the lack of Nox4.

Figure 6

HASMCs were co-transfected with siRNA against Nox4 or a non-targeting siRNA and with an expression vector for cofilin S3A or empty vector 48 hours before mechanical stimulation. After 24 hours of stretch, cells were fixed and stained to estimate cellular alignment as indicated in Materials and Methods. Representative image (B) and bar graphs (mean ± SE) (A) of at least 5–7 independent experiments performed in duplicate are shown. (*) Indicates P<0.05.