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. 2015 Jul 28;5:12667. doi: 10.1038/srep12667

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(A) LFS failed to induce hippocampal LTD in non-stressed control. (B) Stress enabled LFS to induce a stable LTD. (C) Fluoxetine (10 μM) itself had no effect on LTD induction in non-stressed rats. (D) Bath application of fluoxetine failed to prevent stress-facilitated hippocampal LTD. (E) The bar graph summarized the average percentage change of fEPSP amplitude before and 55 min after HFS. Representative traces are shown on the right. *p < 0.05, **p < 0.01, post hoc Turkey’s test after ANOVA (F_{(3, 19)} = 9.954; p < 0.001).