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Variables and two levels
| Independent variable | Low level (−1) | High level (+1) |
|---|---|---|
| A: SLS concentration | 1 | 2 |
| B: ultrasound application time | 1 | 3 |
| C: duty cycle | 50 | 100 |
| D: distance from probe to skin | 0.5 | 1 |
| E: dendrimer concentration | 0.3 | 0.5 |
Notes: Low level (−1) is the minimum concentration of independent variable used during the experiment; High level (+1) is the highest concentration of independent variable used during the experiment.
Abbreviation: SLS, sodium lauryl sulfate.
