Table 2.

Average dice coefficients of hard segmentations were obtained from 22 scans, before and after normalization, comparing our method with that of histogram matching [7]

	WM	GM	CSF	Mean
DSC (input image)	0.8092 ± 0.0190	0.6700 ± 0.0496	0.5225 ± 0.0351	0.6751
DSC (normalized image with hist. matching)	0.8149 ± 0.0196	0.6768 ± 0.0506	0.5309 ± 0.0358	0.6832
DSC (normalized image with hist. normalization)	0.8261* ± 0.0178	0.6884* ± 0.0494	0.5482* ± 0.0362	0.6986

Data layout: mean ± std.

* Statistically significantly larger than the other two (p value 0.05).