Fig. 5.

Effects of calipteryxin and (3’S,4’S)-3’,4’-disenecioyloxy-3’,4’-dihydroseselin on LPS-induced and NF-κB-dependent alkaline phosphatase (SEAP) expression in transfected-RAW 264.7 macrophages as described in “Methods.” The data were derived from three independent experiments and are expressed as the means ± S.D. (***) p <0.001 indicates a significant difference from the LPS-challenged group. (^###) p <0.001 indicates a significant difference from the unstimulated control group. Control (vehicle), LPS; (LPS + vehicle)-treated cells alone; TPCK 30 μM, N-p-tosyl-L-phenylalanyl chloromethyl ketone was used as a positive control