Table I.

Summary of Immunophenotype and Cytogenetic Data

Date	Immunophenotype	Cytogenetics
02/09/07 Diagnosis	CD45dim+, CD117+, CD33dim+, CD34−, CD4dim+, CD41−, CD61−, CD42−, HLA-DR+, CD11b−, CD13−, CD15−, TdT−, MPO− CD45dim+, CD117−, CD33dim+, CD34−, CD4dim+, CD41+, CD61+, CD42+, HLA-DR−, CD11b−, CD13−, CD15−, TdT−, MPO−	BONE MARROW: 46–47,XX,del(13)(q14q14)x2,der(16)t(13;16)(?q31q33:p13.3),t(17;22)(?q25;q13),+21 Abnormal FISH - homozygous deletions of 13q14.3, heterozygous deletion of 13q14.2 (RB1), translocation 13q34;16, trisomy 21 and 17q;22q translocation
02/19/07		PERIPHERAL BLOOD: 46,XX[2] Limited study Normal FISH - disomy 21
03/09/07 Induction I	Normal	BONE MARROW: 46–47,XX,del(13)(q14)x2,der(16)t(13;16)(?q31q33:p13.3),t(17;22)(q25;q13),+21
04/17/07 Induction II	Normal	BONE MARROW: 46,XX, Normal FISH
05/16/07 Intensification I	Normal	BONE MARROW: 46,XX, Normal FISH
06/15/07 Intensification II	Normal	BONE MARROW: 46,XX, Normal FISH
08/10/07 Intensification III Recurrence	CD45+ dim, CD117−, CD33dim+, CD34−, CD19−, CD41+, CD61+, CD42dim+, CD13dim+	BONE MARROW: 46,XX,del(13)(q12q14),del(13)(q14q14)[3]/46,XX Abnormal FISH - homozygous deletions of 13q14.3 and heterozygous deletion of 13q14.2(RB1)
09/14/07 Re-induction I	CD45+, CD33−, CD34−, CD10−, CD19−, glycophorin−, CD41+/−, CD61+/−, CD42 dim+ CD13−	BONE MARROW: 46,XX,del(13)(q12q14),del(13)(q14q14),t(17;22)(q24;q13)[16]/46,XX[ Abnormal FISH - homozygous deletions of 13q14.3, heterozygous deletion of 13q14.2 (RB1), trisomy 21 and 17q;22q translocation
10/01/07 Re-induction II	CD45+, CD33−, CD10−, CD19−, glycophorin−, CD41+, CD61+, CD42+, HLADR+, CD11b−, CD13−	BONE MARROW: 46,XX,del(13)(q12q14),del(13)(q14q14),t(17;22)(?q25;q13) Abnormal FISH - homozygous deletions of 13q14.3, heterozygous deletion of 13q14.2 (RB1) and 17q;22q translocation