Table 2. Low Abundance Proteins identified for subject categories low GFR, high GFR and normal kidney function.
(m/n) - found in m of n samples in a category; bold and underlined - found in all samples in a disease stage-pI category. The confidence interval for protein identification was ≥98% at a p-value of <0.05 for each protein listed.
| pI fraction | Low GFR (n=3) | High GFR (n=3) | Normal (n=2) | |||
|---|---|---|---|---|---|---|
| Protein | (m/n) | Protein | (m/n) | Protein | (m/n) | |
| 6.1 to 5.8 | Hemonexin | (3/3) | Zn-alpha-2-glycoprotein | (1/3) | NA | |
| Transthyretin | (1/3) | |||||
| 5.5 to 5.2 | Alpha-1-microglobulin | (3/3) | Alpha-1-beta-glycoprotein | (1/3) | MAP19 | (2/2) |
| Apolipoprotein A-I | (2/3) | Transthyretin | (1/3) | Zn-alpha-2-glycoprotein | (1/2) | |
| Hemonexin | (3/3) | Zn-alpha-2-glycoprotein | (2/3) | |||
| Transthyretin | (1/3) | |||||
| Vitamin D-binding Protein | (2/3) | |||||
| Zn-alpha-2-glycoprotein | (3/3) | |||||
| 5.2 to 4.9 | Alpha-1-microglobulin | (3/3) | Alpha-1-beta-glycoprotein | (1/3) | Zn-alpha-2-glycoprotein | (1/2) |
| Apolipoprotein A-I | (1/3) | Apolipoprotein A-I | (1/3) | |||
| Retinol-binding Protein 4 | (2/3) | Kininogen-1 | (1/3) | |||
| Uteroglobin | (3/3) | Vitamin D-binding Protein | (1/3) | |||
| Vitamin D-binding Protein | (3/3) | Zn-alpha-2-glycoprotein | (3/3) | |||
| Zn-alpha-2-glycoprotein | (3/3) | |||||
| 4.9 to 4.7 | Alpha-1-beta-glycoprotein | (3/3) | Alpha-1-beta-glycoprotein | (2/3) | Alpha-1-microglobulin | (2/2) |
| Alpha-1-microglobulin | (3/3) | Kininogen-1 | (1/3) | CD59 | (1/2) | |
| Kininogen-1 | (3/3) | Zn-alpha-2-glycoprotein | (3/3) | ITIH4 | (1/2) | |
| Vitamin D-binding Protein | (3/3) | Osteopontin | (1/2) | |||
| Zn-alpha-2-glycoprotein | 100 (3/3) | Zn-alpha-2-glycoprotein | 100 (2/2) | |||