Figure 7.
Influence of increasing selenium concentrations on the cytotoxic anti-neoplastic potency of epirubicin (10−8 M) measured as a function of chemotherapeutic-resistant SKBr-3 mammary carcinoma cell vitality. Legend: (∎) selenium (methylseleninate); and (◆) selenium (methylseleni-nate) in combination with epirubicin (10−8 M). SKBr-3 monolayers were incubated with immunochemotherapeutics over a 72-hour period and cytotoxicity measured as a function of MTT cell vitality relative to matched negative reference controls.