Table 2. Estimated values of parameters as identified in the Ebola modeling articles*.
Reference | Outbreak | Model | R0 estimate | Incubation period, d (SD)† | Infectious period, d (SD) |
---|---|---|---|---|---|
Chowell et al. (1) | DRC 1995 | SEIR‡ | 1.83 (SD 0.06) | 5.3 (0.23) | 5.61 (0.19) |
|
Uganda 2000 |
SEIR‡ |
1.34 (SD 0.03) |
3.35 (0.49) |
3.5 (0.67) |
Lekone and Finkenstädt (4) | DRC 1995 | SEIR, MCMC (vague prior) | 1.383 (SD 0.127) | 9.431 (0.620) | 5.712 (0.548) |
|
DRC 1995 |
SEIR, MCMC (informative prior) |
1.359 (SD 0.128) |
10.11 (0.713) |
6.523 (0.564) |
Legrand et al. (5) | DRC 1995 | Stochastic compartmental model (SEIHFR) | 2.7 (95% CI 1.9–2.8) | ||
|
Uganda 2000 |
Stochastic compartmental model (SEIHFR) |
2.7 (95% CI 2.5–4.1) |
|
|
Eichner et al. (10) |
DRC 1995 |
Incubation period estimate based on parameterized lognormal distribution function |
|
12.7 (4.31) |
|
Ferrari et al. (11) | DRC 1995 | MLE | 3.65 (95% CI 3.05–4.33) | ||
DRC 1995 | Regression | 3.07§ | |||
Uganda 2000 | MLE | 1.79 (95% CI 1.52–2.30) | |||
|
Uganda 2000 |
Regression |
2.13§ |
|
|
White and Pagano (12) | DRC 1995 | MLE | 1.93 (95% CI 1.74–2.78) |
*DRC, Democratic Republic of Congo; MCMC: Markov chain Monte Carlo; MLE, maximum-likelihood estimation; SEIR, susceptible-exposed-infectious-removed; SEIHFR, susceptible-exposed-infectious-hospitalized-funeral-removed. Blank cells indicate that no information was provided from the original study. †The incubation period for Ebola virus is believed to be the same as its latent period, i.e., infected persons become infectious only when symptomatic. ‡Combination differential equation model and Markov chain model. §Neither CIs nor SDs were provided in the study.