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. 2015 Aug;21(8):1429–1432. doi: 10.3201/eid2108.140343

Table. Serologic, immunohistopathologic, and molecular test results for patients with infective endocarditis caused by Bartonella spp. or Coxiella burnetii, Brazil*.

Patient no., by infection type Serum IgG ≥800 by IFA† Immunohistochemical analysis of cardiac valve vegetation
Microorganism by histologic analysis PCR‡ Species of Bartonella
Bartonella spp. C. burnetii
Bartonella spp.
1 + + Neg Gram-negative coccobacilli + B. quintana
2 + + Neg Gram-negative coccobacilli + B. henselae
3 + + Neg None + B. henselae
4 + NA NA NA Neg NA
5 + + Neg Gram-negative coccobacilli + NA
6 + + Neg Gram-negative coccobacilli + B. quintana
7 + NA NA NA + B. henselae
8 + NA NA NA + NA
9 + NA NA NA Neg NA
10 + + Neg Gram-negative cocci + B. henselae
C. burnetii Serum anti–phase I IgG
≥800 by IFA§ Immunohistochemical analysis of cardiac valve vegetation
Microorganism by histologic analysis PCR‡ Q fever endocarditis (6)
Bartonella spp. C. burnetii
11 + Neg + Small gram-negative coccobacilli + Definite
2A criteria
12 + Neg + None + Definite
2A criteria
13 + Neg + None + Definite
2A criteria
14 + NA NA NA + Definite
2B criteria¶

*IFA, immunofluorescence assay; +, positive; Neg, negative; NA, material not available for analysis.
¶Serologic result >6,400 and vegetation on ecocardiography.
†B. henselae or B. quintana.
‡Serum or tissue sample.
§C. burnetii.