Table 2. PCR results in S. mansoni egg-positives and-negatives.
Country | Microscopy | PCR | Test agreement (κ) | ||
---|---|---|---|---|---|
Number of stool samples taken into account | Egg-based S. mansoni infection status | Percentage PCR-positives (n) | Median Ct-value (IQR) a | ||
Senegal | 1 | - | 45.2% (38/84) | 28.4 (23.4–33.9) | 76.6% (0.500) |
+ | 92.9% (105/113) | 21.1 (20.0–23.0) | |||
2 | - | 35.5% (22/62) | 32.0 (28.2–34.6) | 81.7% (0.561) | |
+ | 89.6% (121/135) | 21.6 (20.0–23.3) | |||
Kenya | 1 | - | 19.4% (119/614) | 31.2 (24.2–35.2) | 81.8% (0.536) |
+ | 87.0% (127/146) | 22.4 (20.6–26.7) | |||
2 | - | 14.4% (81/563) | 33.3 (25.2–35.4) | 85.1% (0.642) | |
+ | 83.8% (165/197) | 23.2 (21.0–29.0) | |||
3 | - | 11.8% (63/536) | 34.1 (26.3–35.8) | 86.3% (0.680) | |
+ | 81.7% (183/224) | 23.4 (21.1–30.7) |
a Median and IQR (interquartile range, calculated using Tukey’s hinges) are given for egg-positive and/or PCR-positive individuals only.