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. Author manuscript; available in PMC: 2016 Jul 16.
Published in final edited form as: Mol Cell. 2015 Jul 2;59(2):163–175. doi: 10.1016/j.molcel.2015.05.038

Figure 3. Lack of strand bias of URA3 mutations located near ARS306 in the DBY747 pol3-L612M msh2Δ strain.

Figure 3

(A) Hot spot mutations in URA3 observed in OR1 in the DBY747 pol3-L612M msh2Δ strain. The URA3 coding region is integrated ~ 1.2 kb to the left of ARS306 on chromosome 3 as described in Figure 2. (B) Hot spot mutations in URA3 near ARS306 observed in OR2 in the pol3-L612M msh2Δ strain. The orientation of URA3 is reversed from that in (A). The sum of all hotspot mutations for the leading or the lagging DNA strand is given on the right.

See also Figure S4 and Table S3.

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