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. 2015 Jul 28;10(7):e0134089. doi: 10.1371/journal.pone.0134089

Fig 2. Blood glucose levels and liver glycogen storage in chow and HFD-fed C57Bl/6 and BALB/c mice.

Fig 2

(A) Fasting blood glucose levels were significantly higher in chow-fed C57Bl/6 mice compared with chow-fed BALB/c mice. Serum insulin levels did not differ, while HbA1c was significantly higher in chow-fed C57Bl/6 mice compared with chow-fed BALB/c mice at 32 weeks of age. (B) Fasting blood glucose levels were significantly higher in HFD-fed C57Bl/6 mice compared to HFD-fed BALB/c mice. Serum insulin levels were significantly higher in HFD-fed C57Bl/6 mice compared to HFD-fed BALB/c mice, with no difference in HbA1c at 32 weeks of age. (C) Representative images of PAS staining on paraffin-embedded liver tissue sections (original magnification x10, scale bar = 100μm). Glycogen stores were significantly higher in liver of HFD-fed C57Bl/6 mice compared to HFD-fed BALB/c mice at 32 weeks of age. The results are shown as the means ± SEM for 9–10 animals per group. *p<0.05. The results are representative of two experiments.