Figure 6.

siRNA luciferase screen for the identification of protein kinases that modulate AR-mediated transcription. Dual luciferase assays were performed after cotransfection of the indicated siRNAs, and data were presented as heatmaps. Asterisks denote significant differences between cells transfected with target siRNAs and control siRNAs (Student's t test; *, P < .05, n = 3). Triangles indicate androgen-insensitive proteins (0.67 > ln [AS/AD] > −0.67). Red check marks indicate known AR-interacting proteins.