Table 1.
Comparison between the Lipoylation and Biotinylation Systems of S. aureus and S. pyogenes
|
S. aureus |
S. pyogenes |
||||
|---|---|---|---|---|---|
| Protein | Accessiona | Protein | Accessiona | ||
| Lipoylationb | Lipoate scavenging | LplA1 | CAG42736 | LplA1 | CAM30328 |
| LplA2c | CAG42075 | LplA2c | CAM30198 | ||
| LplA3 | CAG43266 | – | – | ||
| LplA4 | CAG42323 | – | – | ||
| Lipoyl-carrier proteins | – | – | AcoC | CAM30333 | |
| – | – | AcoL | CAM30332 | ||
| DBT | CAG43237 | – | – | ||
| DLAT | CAG42804 | – | – | ||
| DLST | CAG43130 | – | – | ||
| GcvH | CAG42548 | – | – | ||
| GcvH-Lc | CAG42072 | GcvH-Lc | CAM30195 | ||
| Biotinylationd | Biotin scavenging | BPL | BAB57618 | BPL | CAM30079 |
| Biotin-carrier proteins | BCCP (ACC) | BAB57689 | BCCP (ACC) | CAM29699 | |
| – | – | BCCP (OAD) | CAM30229 | ||
| PC | BAB57276 | – | – | ||
ACC, acetyl-CoA carboxylase; AcoC, dihydrolipoamide acetyltransferase (AoDH-E2); AcoL, dihydrolipoamide dehydrogenase (AoDH-E3); BCCP, biotin carboxyl carrier protein; BPL, biotin protein ligase; DBT, dihydrolipoamide branched chain transacylase E2 (BCDH-E2); DLAT, dihydrolipoamide S-acetyltransferase (PDH-E2); DLST, dihydrolipoamide S-succinyltransferase (KDH-E2); OAD, oxaloacetate dehydrogenase; PC, pyruvate carboxylase.
a
GenBank accession numbers.
b
Based on Spalding and Prigge (2010).
c
Operon-encoded proteins.
d
Based on Fall (1979).