Examples of spectral-domain optical coherence tomography (SD OCT) of affected left eyes of the patients with optic nerve hypoplasia (ONH) (left) and age-, gender-, ethnicity-, and refraction-matched healthy controls (right). The optic nerve head scans of patients with ONH demonstrated small disc and cup diameters, and cup depth. The horizontal macula scans of the patients with ONH (bottom left and top left) demonstrate a thin retina, flat foveal pits, a thin retinal nerve fiber layer (RNFL) and ganglion cell layer (GCL), continuation of the inner plexiform layer (IPL) and inner nuclear layer (INL), a domed central area of ONL, and absence of the upward deflection of the ellipsoid line in the center of the fovea in patients with ONH. E = ellipsoid.