Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
IC50 values of benzimidazole and pyrimidine compounds for inhibition of yeast and rat intestinal α-glucosidase.
| Compounds |
IC
50
(µM)
|
|
|---|---|---|
| Yeast | Rat | |
| 4a | 54.6±2.2 | na |
| 4b | na | na |
| 4c | 15.2±1.7 | 48.5±2.3 |
| 4d | 9.1±1.2 | 36.7±2.9 |
| 5a | 49.6±2.7 | na |
| 5b | na | na |
| 5c | 11.9±1.5 | 35.9±2.3 |
| 5d | 8.3±0.9 | 21.8±1.7 |
| 5e | na | na |
| Acarbose | 120.3±2.8 | 37.5±1.4 |
na: no activity
