Table 3.

Possible H-bond interactions of Amprenavir with different conformations of the HIV-1 PR

	Ile50(B)	Gly48(B)	His48(B)	Asp29(B)	Asp30(B)	Asp25(B)	Asp25(A)	Il50(A)	Asp29(A)	Gly27(A)	Gly27(B)	Asp30(A)	Thr80(A)	Arg8(A)	Leu50(B)	Leu50(A)	Val82(A)	Arg8(B)	Gly48(A)
2PQZ	2.12						2.14	1.91
2Q5K	2.07	2.48			2.21	1.69						2.37
3EKV					1.83		1.81			2.08
3MXD	2.4					2.24		2.36
3O9F				1.98						1.87							3.12
3O9I					2.24		1.9		1.99
3SA5							2.67	2.05	3.01		2.19
3SA8	1.96			1.85				2.01		1.88	2.18
3SAB	2.34			2.04		1.74		2.08			2.04	2.28
4DJP	2.26						1.78			1.98		2.12
4DQB					2.01	2.26			2.42			2.06
2PSU					2.31	1.81				1.99		2.37
2Q54				2.4	1.9	2.61	1.86				2.12	2.13
3EKX	2.28			2.34		2.39, 2.4
3MXE	2.19						2.25	1.93	1.98
3O9G	1.96							1.88		2.02	2.20
3SA3					2.05	1.84				2.09		4.9
3SA6	2.35				1.99	2.04				2.32
3SA9	2.22					1.86		2.16			2.36	2.41		2.04
3SAC	2.42					2.81		2.12
4DJQ	2.31			2.04		1.86		1.86			2.18
2PSV							2.34			2.13
2Q55							2.46
3EM3				1.94		1.75						2.33	2.15		2.05	2.06
3NLS				1.9			1.99				2.32	2.02
3O9H	2.43					1.71		2.09					2.71				2.77	2.43
3SA4	1.94					2.4		2.24		2.03							2.12
3SA7	2.49	1.91		2.67	2.14						2.18
3SAA							2.33												1.94
4DJO	2.15			1.96		2.21		2.35						2.58
4DJR	1.92			1.89		2.14		1.75
1AJV	2.32					1.94
1BWA				2.79			2.7
1CPI	1.84							2.17		1.85	1.81
1HPV	2.11					2.34		2.31				2.28
1T3R						1.83		2.27		2.38			2.23
1XL5							1.97	2.29, 2.21			2.08
1A8G	2.19	2.10, 1.91
1A9M	2.32		2.22	2.22	1.89	2.07		2.41
1BWB	2.11
1AJX	2.26				2.32		2.2	2.2	2.13
1BV9	1.98					2.39		2.11		2.07
1DIF								2.15				3.25							2.88
1GNO					1.81		1.96		1.94			1.99
1IDB					2.04		1.78
1MUI	2.04					1.77		2.38
1T7J	1.82				2.12	1.92		2.17
1XL2	2.34	1.95
2I0A					1.91		1.95			2.14		2.06
2I0D	2.11	1.87		2.32	1.79			1.89
Apo								2.53