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. 2015 Summer;14(3):811–824.

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© 2015 by School of Pharmacy, Shaheed Beheshti University of Medical Sciences and Health Services

This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Effects of four-training trials on escape latency (A) and traveled distance (B) in L-NAME and Aβ pretreated animals. There was a significant reduction in escape latency and traveled distance in all the groups through four days of training (Figures 1 A and B). There was a significant difference between the first and the fourth day of training, measured by two factors of escape latency and traveled distance except in (Aβ + L-NAME 1 μg/side) treatment group which the traveled distance didn’t decrease significantly from first day to the fourth day of training. The swimming speed was consistent during the four training days in all of the groups (data not shown). Each value explains Mean ± S.E.M for 6-8 rats. (*P < 0.05; **P < 0.01; ***P < 0.001 shows difference between the first and the fourth days of training).