Table 2.
Effect of different extract of L. reticulata on Formalin induced Paw edema test.
| Treatment |
Increase in paw volume
|
% Inhibition of Edema
|
|||||
|---|---|---|---|---|---|---|---|
| (mg/Kg) | 0 h | 1 h | 2 h | 4 h | 1 h | 2 h | 4 h |
| Control | 0.66±0.87 | 1.24±0.51 | 1.62±0.22 | 2.36±0.88 | - | - | - |
| EA (400) | 0.56±0.76 | 1.02 ±0.49 | 1.13±0.91 | 1.41 ±0.72 | 18±0.11c | 30±0.2c | 40±0.21c |
| EA (600) | 0.55±0.38 | 0.82 ±0.97 | 0.87 ±0.18 | 0.93±0.17 | 33.87±0.21b | 46.29±0.3b | 60.59±0.43b |
| Meth(400) | 0.63±0.51 | 1.14 ±0.88 | 1.40±0.19 | 1.86±0.15 | 8±0.19e | 13.58±0.1d | 21.18±0.19e |
| Meth(600) | 0.61±0.44 | 1.09 ±0.71 | 1.31 ±0.23 | 1.58 ±0.63 | 12.09±0.1d | 19.13±0.2d | 33.05±0.23cd |
| Water(400) | 0.64±0.57 | 1.18 ±0.73 | 1.51 ±0.92 | 2.15 ±0.75 | 5±0.12e | 7±0.18e | 9±0.16f |
| Water(600) | 0.63±0.97 | 1.17 ±0.61 | 1.56±0.84 | 2.19 ±0.95 | 6±0.1e | 4±0.15e | 7±0.13f |
| Diclofenac Sodium (50) |
0.49±0.66 | 0.60±0.11 | 0.65±0.66 | 0.68±0.59 | 52±0.26a | 60±0.32a | 71±0.4a |
F-value 323.85
Note: The Values within each column represent, Mean ± SE followed by same letters in superscript are not significantly different from each other (P< 0.0001). Data analysed by GLM procedure with Duncan’s multiple range test (DMRT) using SAS®.
at α = 0.05