Figure 1.

Data are means ± SD. (a) Central pulse wave velocity (PWV) before (Pre) and after (Post) 8 wks of simvastatin (n = 100) or placebo treatment (n = 100); ^∗ P < 0.05 compared to Pre within a group. (b) Changes (Post-Pre) in central PWV of participants who completed the simvastatin intervention with no development of statin-related muscle symptoms (nonmyalgics; n = 76) compared with those who reported muscle symptoms with daily simvastatin treatment (myalgics; n = 34); P = 0.51 between groups.