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. 2015 Jul 29;5:12593. doi: 10.1038/srep12593

Figure 2. Condylar subchondral bone and cartilage changes of 4-week and 8-week control rats (Con) and experimental rats (Exp) treated with physiological saline (Veh), non-selective β-blocker propranolol (20 μg/g, PRO), or β-adrenergic receptors agonist isoproterenol (5 μg/g, ISO).

Figure 2

A: Representative images of micro-computed tomography, H&E and safranin O staining of the mandibular condye. B: Analysis of bone mineral density (BMD) and different parameters representing trabecular microstructures of the condylar subchondral bone based on the reconstructed micro-computed tomography images. C: Comparison of the values of the thickness of fibrous, proliferative, hypertrophic, and total layers of the condylar cartilage and the percent area of safranin O staining. *P < 0.05: vs age-matched control, **P < 0.01: vs age-matched control; #P < 0.05: vs age-matched vehicle-treated counterpart, ##P < 0.01: vs age-matched vehicle-treated counterpart.