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. 2015 Jul 29;5:12593. doi: 10.1038/srep12593

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A: Representative images of H&E and TRAP staining. B: Bone histomorphometric analysis of bone volume fraction (BVF), trabecular thickness (Tb.Th), trabecular number (Tb.N) and trabecular separation (Tb.Sp). C: Bone histomorphometric analysis of osteoclast number (Oc.N) and the percentage of osteoclast surface area with respect to bone surface (Oc.S/BS). D: Real-time PCR analysis of the mRNA expression of Cathepsin K (CasK), TRAP and calcitonin receptor (CTR) in the condylar subchondral bone. *P < 0.05: vs age-matched control, **P < 0.01: vs age-matched control; ^#P < 0.05: vs age-matched vehicle-treated counterpart, ^##P < 0.01: vs age-matched vehicle-treated counterpart.