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. 2015 Jul 29;5:12648. doi: 10.1038/srep12648

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Copyright © 2015, Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Dots in each plot represent the significant test statistics of eRNAs matching to miRNAs (denoted by red circles) or other RNAs (denoted by blue triangles). Significances were estimated using a two-proportion t-test, which tests the eRNA matches to miRNA versus other RNAs against random intergenic control data. The trend lines are least rectangles regression for miRNA data (red) and other RNA data (blue). For presentation, all axes are limited to 0.35 and represent the ratio of hits to a specific RNA family to the total number of significant hits from Rfam.