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. Author manuscript; available in PMC: 2015 Jul 29.
Published in final edited form as: Clin Biochem. 2012 Jun 16;45(0):999–1011. doi: 10.1016/j.clinbiochem.2012.06.007

Table 1.

Body of evidence summary table: venipuncture (versus catheter).

Study (Quality and Effect Size Ratings) Population/Sample Setting Time period Results (Blood Culture Contamination Rates)
Beutz 2003
 - Good
 - Moderate
300 paired blood cultures from 119 patients - medical ICU Barnes - Jewish Hospital, St. Louis, MO: 1,000 bed university - affiliated teaching hospital 9 months (02/2001 – 10/2001) Venipuncture: 3.7%
Catheter: 6.7%
OR = 1.88 (CI: 0.88 – 3.99)
DesJardin 1999
 - Good
 - Moderate
551 paired blood cultures from 185 patients – oncology ward New England Medical Cente, Boston, MA; 300 - bed tertiary care university - affiliated hospital 22 months (08/1994 – 06/1996) Venipuncture: 2.4%
Catheter: 4.4%
OR = 1.88 (CI: 0.95 – 3.74)
Everts 2001
 - Good
 - Substantial
1,408 pairs of concurrent catheter-drawn and venipuncture samples Tertiary - care medical setting; Duke University School of Medicine, Durham, NC 24 months (01/1997 – 12/1998) Venipuncture: 1.8%
Catheter: 3.8%
OR = 2.12 (CI: 1.32 – 3.41)
Martinez 2002
 - Good
 - Substantial
499 paired blood cultures from 271 patients - surgical and cardiothoracic ICUs New England Medical Center, Boston, MA; 300 - bed tertiary care university - affiliated hospital 34 months (11/1994 – 08/1997) Venipuncture: 1.6%
Catheter: 4.0%
OR = 2.57 (CI: 1.13 – 5.89)
Mcbryde et al. (2005)
- Good
- Substantial
962 paired venipuncture and catheter - drawn blood cultures from same patient – multiple wards Mater Misericordiae Hospital, Brisbane, Queensland Australia; 280 beds; Teaching hospital 44 months (01/1998 - 08/2002) Venipuncture: 2.6%
Catheter: 13%
OR = 5.60 (CI: 3.61 – 8.69)
Norberg 2003
 - Good
 - Substantial
4,108 total blood cultures – pediatric emergency department
Catheter: 2108 Venipuncture: 2000
Children’s Hospital Medical Center of Akron, Akron, OH 12 months (01/1999 - 12/1999) Venipuncture: 2.8%
Catheter: 9.1%
OR = 3.46 (CI: 2.55 – 4.69)
Qamruddin et al. (2007)
 - Fair
 - Moderate
1,138 total blood culture samples – adult patients from multiple wards
Venipuncture: 979
Catheter: 159
Manchester Royal Infirmary, Manchester, UK. 2 months (02/2006 - 04/2006) Peripheral vein: 7.3%
Catheter: 10.7%
OR = 1.53 (CI: 0.88 – 2.68)
Ramsook et al. (2000)
 - Fair
 - Substantial
1,722 total blood cultures – pediatric emergency room
Venipuncture: 427
Catheter: 1295
Texas Children’s Hospital; Houston University - affiliated Houston, Texas 6 months (02/1999 - 07/1999) Venipuncture: 1.2%
Catheter: 3.4%
OR = 2.97 (CI: 1.17 – 7.54)
Weddle 2011
 - Good
 - Substantial
3,025 total blood cultures - pediatric emergency department
Venipuncture: 1229
Catheter: 1796
Children’s Mercy Hospitals and Clinics, Kansas City, MO. 263-bed tertiary children’s hospital. 12 months (9/2008 - 8/2009) Venipuncture: 2.4 (29/1229)
Catheter: 6.7% (120/1796)
OR = 2.96 (CI 1.96 – 4.47)
BODY OF EVIDENCE RATINGS # Studies by Quality and Effect Size Ratings
5 Good/Substantial
1 Fair/Substantial
2 Good/Moderate
1 Fair/Moderate
Consistency YES
Overall Strength HIGH

Bibliographic information for all studies is provided in Appendix C.