Table 5.
The distributions of haplotype frequencies of SNPs −9C>T and 368A>G in H2B.W gene in infertile patients with azoospermia or sever oligozoospermia and fertile men
| Haplotype | Fertile men | Infertile patients | P valuea | OR (95% CI)a | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Total (n=60) | Total (n=92) | Azoospermia(n=46) | Severe oligozoo spermia (n=46) | 1 | 2 | 3 | 1 | 2 | 3 | |
| CA | 33.30%(n=20) | 30.40%(n=28) | 34.70%(n=16) | 26.00%(n=12) | 0.693 | 0.756 | 0.688 | Reference | Reference | Reference |
| TA | 30%(n=18) | 34.80%(n=32) | 30.40%(n=14) | 39.10%(n=18) | 0.565 | 0.954 | 0.302 | 1.27(0.563-2.866) | 0.972(0.373-2.573) | 1.667(0.632-4.392) |
| CG | 26.70%(n=16) | 29.30%(n=27) | 30.40%(n=14) | 28.20%(n=13) | 0.664 | 0.857 | 0.562 | 1.205(0.519-2.802) | 1.094(0.413-2.894) | 1.354(0.487-3.769) |
| TG | 10%(n=6) | 5.40%(n=5) | 4.30%(n=2) | 6.50%(n=3) | 0.441 | 0.321 | 0.819 | 0.595(0.159-2.224) | 0.417(0.074-2.350) | 0.883(0.175-3.965) |
SNP; Single nucleotide polymorphisms, OR; Odd ratio, CI; Confidence interval, a; Controls vs. 1; Total infertile patients, 2; Azoospermia and 3; Sever oligozoospermia.