Table 6.
The distributions of haplotype frequencies of SNPs −9C>T and 368A>G in H2B.W gene in azoospermia according to testicular biopsy
| Haplotype | Azoospermia (n=46) | P valuea | OR (95% CI)a | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Men with hypospermatogenesis(n=8) | CMA(n=17) | SCOS (n=21) | 1 | 2 | 3 | 1 | 2 | 3 | |
| CA | 62.50%(n=5) | 17.60%(n=3) | 38.10%(n=8) | 0.246 | 0.519 | 0.104 | Reference | Reference | Reference |
| TA | 25%(n=2) | 52.90%(n=9) | 14.30%(n=3) | 0.06 | 0.952 | 0.029 | 7.5(0.921-61.047) | 0.937(0.114-7.728) | 0.125(0.019-0.805) |
| CG | 12.50%(n=1) | 23.50%(n=4) | 42.90%(n=9) | 0.155 | 0.15 | 0.851 | 6.6670.487-91.331) | 5.625(0.537-58.909) | 0.844(0.143-4.974) |
| TG | 0 | 5.90%(n=1) | 4.80%(n=1) | 1 | 1 | 0.532 | 2.69E+09(0.000- .) | 1.01E+09(0.000-.) | 0.375(0.017-8.103) |
SNP; Single nucleotide polymorphisms, CMA; Complete maturation arrest, SCOS; Sertoli cell only syndrome, OR; Odd ratio, CI; Confidence interval, a; Men with hypo spermatogenesis vs. 1; CMA, 2; SCOS and 3; SCOS vs. CMA.