Table 1.
Microglia | Müller cells | Ganglion cells | ||||
---|---|---|---|---|---|---|
4 h | 16 h | 8 h | 72 h | 8 h | 16 h | |
NOX1 | ||||||
N | 1.01 ± 0.01 | 1.01 ± 0.00 | 1.00 ± 0.00 | 1.00 ± 0.01 | 1.00 ± 0.00 | 1.00 ± 0.00 |
H | 1.31 ± 0.06** | 3.06 ± 0.28** | 0.90 ± 0.13 | 1.63 ± 0.11** | 2.90 ± 0.25* | 2.45 ± 0.47* |
NOX2 | ||||||
N | 1.00 ± 0.00 | 1.02 ± 0.02 | 1.04 ± 0.04 | 1.01 ± 0.01 | 1.02 ± 0.01 | 1.06 ± 0.04 |
H | 2.15 ± 0.21** | 0.93 ± 0.07 | 0.87 ± 0.11 | 1.16 ± 0.18 | 1.26 ± 0.52 | 1.12 ± 0.21 |
NOX4 | ||||||
N | 1.01 ± 0.01 | 1.01 ± 0.01 | 1.00 ± 0.00 | 1.00 ± 0.01 | 1.03 ± 0.02 | 1.01 ± 0.00 |
H | 1.66 ± 0.11*** | 1.77 ± 0.04*** | 0.96 ± 0.04 | 0.70 ± 0.14 | 1.02 ± 0.10 | 1.01 ± 0.12 |
Values are mean ± SEM. n = 3 to 4 independent experiments and performed in triplicate
N normoxia (21 % O2), H hypoxia (0.5 % O2)
*P < 0.05, **P < 0.01, and ***P < 0.001 to normoxia control