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. 2015 Jul 30;12:136. doi: 10.1186/s12974-015-0363-z

Table 1.

mRNA levels of NOX1, NOX2, and NOX4 in primary cultures of rat retinal microglia, Müller cells, and ganglion cells exposed to normoxia and hypoxia

Microglia Müller cells Ganglion cells
4 h 16 h 8 h 72 h 8 h 16 h
NOX1
 N 1.01 ± 0.01 1.01 ± 0.00 1.00 ± 0.00 1.00 ± 0.01 1.00 ± 0.00 1.00 ± 0.00
 H 1.31 ± 0.06** 3.06 ± 0.28** 0.90 ± 0.13 1.63 ± 0.11** 2.90 ± 0.25* 2.45 ± 0.47*
NOX2
 N 1.00 ± 0.00 1.02 ± 0.02 1.04 ± 0.04 1.01 ± 0.01 1.02 ± 0.01 1.06 ± 0.04
 H 2.15 ± 0.21** 0.93 ± 0.07 0.87 ± 0.11 1.16 ± 0.18 1.26 ± 0.52 1.12 ± 0.21
NOX4
 N 1.01 ± 0.01 1.01 ± 0.01 1.00 ± 0.00 1.00 ± 0.01 1.03 ± 0.02 1.01 ± 0.00
 H 1.66 ± 0.11*** 1.77 ± 0.04*** 0.96 ± 0.04 0.70 ± 0.14 1.02 ± 0.10 1.01 ± 0.12

Values are mean ± SEM. n = 3 to 4 independent experiments and performed in triplicate

N normoxia (21 % O2), H hypoxia (0.5 % O2)

*P < 0.05, **P < 0.01, and ***P < 0.001 to normoxia control