Fig. 1.

siRNA library screening of cell cycle regulators. NGP cells (a) and IMR-32 cells (b) were transfected with the siRNA library including negative controls (scrambled siRNA) and their growth was assessed using the xCELLigence system. The data shown in the graphs represent the cellular proliferation measurements recorded at 48 h post transfection. The data are depicted as Z score values (Additional file 1: Table S1), which represent the number of standard deviations from the average for every measurement. Positive Z score values indicate an increase in cell growth, whereas negative values represent a decrease in cell growth.