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. Author manuscript; available in PMC: 2015 Aug 1.
Published in final edited form as: J Autoimmun. 2014 Jan 2;52:64–73. doi: 10.1016/j.jaut.2013.12.014

Figure 7. Down modulated T cell proliferation in splenocytes obtained from recombinant IgG2a Fc multimers (M045)-treated mice is associated with decreased levels of pro-inflamatory cytokines and elevated level of IL-4 and IL-10.

Figure 7

The cytokines IL-2 (a&e), INF-γ (b&f), IL-10 (c&g) and IL-4 (d&h) were measured in the supernatants obtained from the proliferation assay cultured in which anti-CD3 and tAChR were used to stimulate T cells. The values in the bar diagram represents the mean ± SEM of duplicate values of two separate experiments. Significance at p<0.05. *, compared to PBS; ♠, compared to IVIG.