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. 2015 Jun 12;19(3):177–185. doi: 10.1590/bjpt-rbf.2014.0088

Table 1. Maximum response to noradrenaline, in absence or presence of indomethacin or L-NAME, obtained in two rings, one with and the other without endothelium, of the same thoracic aorta from sedentary and trained rats, submitted or not to stress.

Inhibitor Groups
Sedentary Trained Stressed Trained/Stressed
+E –E +E –E +E –E +E –E
Without 3.94±0.15 (n=9) 5.25 ± 0.30† (n=9) 2.82 ± 0.11* (n=10) 4.92 ± 0.47† (n=10) 2.80 ± 0.10* (n=9) 5.28 ± 0.31† (n=8) 2.97 ± 0.21* (n=10) 5.12 ± 0.59† (n=8)
Indomethacin 2.61 ± 0.13# (n=8) 5.10 ± 0.50† (n=8) 2.99 ± 0.29 (n=7) 4.95 ± 0.26† (n=7) 1.86 ± 0.18*# (n=8) 4.99 ± 0.29† (n=8) 2.80 ± 0.18 (n=8) 4.91 ± 0.19† (n=8)
L-NAME 5.23 ± 0.26# (n=7) 4.95 ± 0.29 (n=7) 5.28 ± 0.30# (n=8) 5.11 ± 0.19 (n=9) 5.55 ± 0.38# (n=8) 5.57 ± 0.35 (n=7) 4.42 ± 0.41# (n=8) 5.28 ± 0.54† (n=8)

Maximum response in gram of tension; (+E): with endothelium; (-E): without endothelium; stress: immobilization for 2 h; physical training: 60-min swimming session/5 days/week during 8 weeks, with 5% body weight load attached to the chest. *P<0.05 relate to sedentary group. #P<0.05 presence of inhibitor vs absence of inhibitor. †P<0.05 rings without endothelium vs rings with endothelium; values are means ± SEM; (n) = number of animals; the data were compared by two-way ANOVA and complemented with the multiple comparisons Tukey's test.