Table 1.

Sample sizes of records and practices as determined by different MDO rates

Scenario	True MDO rate (%)	Number of practices (phases 1 + 2)	Number of records per practice	Total number of records reviewed	Expected number of detected MDOs	95 % CI on the estimated MDO rate
1	1	50	250	12500	100	0.4-1.6
2	5	50	100	5000	200	3.5-6.5
3	10	40	100	4000	320	7.7-12.3