Table 2.
Location of putative alternative polyadenylation signals (PS) in the 3' UTR of AMBN cDNA sequences
| Species | Length | PS1 | PS2 | PS3 | PS4 | PS5 |
|---|---|---|---|---|---|---|
| 3'UTR | ATTAAA | AATAAA | AATAAA | ATTAAA | AATAAA | |
| Human | 553 | 106-111 | 129-134 | 189-194 | 415-420 | 536-541 |
| Bushbaby | 483 | 77-83 | 100-105 | 157-162 | 344-349 | 466-471 |
| Tree shrew | 553 | 106-111 | 129-134 | 189-194 | 412-417 | 536-541 |
| Mouse | 543 | - | 127-132 | 184-189 | 403-408 | 526-531 |
| Squirrel | 539 | 105-110 | 128-133 | 188-193 | 406-411 | 521-526 |
| Rabbit | 549 | 106-111 | 129-134 | 189-194 | 410-415 | 532-537 |
| Cow | 555 | 106-111 | 129-134 | 189-194 | 419-424 | 538-543 |
| Horse | 556 | 106-111 | 129-134 | 189-194 | - | 539-544 |
| Dog | 557 | 107-112 | 130-135 | 190-195 | - | 540-545 |
| Microbat | 513 | - | 109-114 | 169-174 | 377-382 | 497-502 |
| Elephant | 556 | - | 126-131 | 186-191 | - | 537-542 |
| Opossum | 540 | 121-126 | - | 209-214 | 495-500 | 520-525 |
| Platypus | 441 | 116-121 | - | - | - | 426-431 |
| Caiman | 493 | - | 95-100 | 298-303 | - | 475-480 |
TGA-------------PS1---PS2--------PS3-----------------------PS4--------------PS5--AAAAAAA
The PS are given for 13 representative species of the main mammalian lineages and the crocodile. Bottom: schematical representation of PS locations on the human AMBN sequence from the stop codon (TGA) to the poly(A); an hyphen represents 10 nucleotides