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. 2015 Jul 30;15:94. doi: 10.1186/s12876-015-0325-z

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© Lu et al. 2015

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 10 — Diagram that summarizes the possible underlying mechanisms of key changes in gene expression and pathophysiology in adult male mice with hepatocyte-specific activation of Ikk2 (Liv-Ikk2ca). Genes that are active or induced in Liv-Ikk2ca mice are in green shape, whereas genes that are inactive or unchanged in Liv-Ikk2ca mice are in red shape. Pathways/responses that are activated in Liv-Ikk2ca mice are marked with (+), whereas pathways/responses that are inhibited or unchanged in Liv-Ikk2ca mice are marked with (−)