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Tumorigenicity of lung adenocarcinoma in Tg-SPC-SFN+/− mice
| Genotype | Wild type | Tg-SPC-SFN+/− | ||
|---|---|---|---|---|
| i.p. | Saline | NNK | Saline | NNK |
| Nodule count | ||||
| 0 | 7 | 24 | 5 | 12 |
| 1 | 0 | 3 | 1 | 10 |
| 2 | 0 | 0 | 1 | 0 |
| 3 | 0 | 0 | 0 | 1 |
| Total | 7 | 27 | 7 | 23 |
| Proportion of mice with tumor(s) | 0 | 11.1 % | 28.6 % | 47.8 % |
